摘要
目的评价液基细胞学（TCT）及阴道镜检查联合应用于宫颈癌筛查的价值，探索一种适合我区经济水平的高效简捷的宫颈癌及癌前病变的筛查方法。方法2008年1月-2010年12月经我院普查的新会区已婚妇女18601人，随机分为两组，其中A组11104人行宫颈TCT检查及阴道镜活检，B组7497人进行传统宫颈刮片检查及阴道镜活检，对比两组的检出阳性率、宫颈上皮内瘤变（CIN）I）2J2病变的检出率及与病理诊断CIN的符合率。结果TCT应用于宫颈癌及癌前病变筛查检出阳性率为6．75％，与病理诊断CIN的符合率为81.3％，联合阴道镜检查经病理活检证实为CIN以上病变的检出率为2．18％，均明显高于传统的宫颈刮片法联合阴道镜检查。结论TCT联合阴道镜检查进行宫颈癌及癌前病变普查是适合我区经济水平的高效简捷的筛查方法，可为早发现、早诊断、早治疗宫颈癌及癌前病变及制定相关预防、干预对策提供依据。
Objective To study utility of Thin Prep cell test（TCT） and colposcope in screening of cervical cancer and to search for an economical and more sensitive way in screening of cervical cancer in Xinhui distict. Methods The study involved 18601 married women in Xinhui Distric who were screened in our hospital from Jan.2008 to Dec.2010, they were randomized into two groups, group A （11104 cases） were screened by TCT and colposcope, group B（7497 cases） were screened by traditional cervical-cell smears and colposcope, to compare the positive rates and the rates of conforming to the diagnosis of pathology cervical intraepithelial neoplasia （CIN） between two methods. Results In group A, 6.75% was the positive rate by using only TCT to screening, 2.18% was the rate of the diagnosis of pathology CIN and above it by using TCT and colposcope to screening, the rate of conforming to the diagnosis of pathology CIN was 81,3 %, all the rates were remarkably higher than those screened by traditional cervical-cell smears and colposcope in group B. Conclusion TCT combined with colposcope is a more sensitive and economical method in screening of cervical cancer and CIN in Xinhui distict, it provides evidence for earlier finding, diagnosis and treatment, and for setting up preventive measurements and intervention for cervical cancer and CIN.
出处
《国际医药卫生导报》
2011年第24期3007-3009,共3页
International Medicine and Health Guidance News
关键词
宫颈癌
宫颈上皮内瘤变
液基细胞学
阴道镜
普查
Cervical cancel
Cervical intraepithelial neoplasia
Thin Prep cell tesl
Colposcop
Screening
