摘要
目的:探讨米非司酮配伍依沙吖啶与单纯依沙吖啶终止中期妊娠的临床效果。方法:总结本院2008年10月～2010年5月收治的65例妊娠16～24周患者的资料,将其随机分为观察组和对照组,观察组40例,口服米非司酮片50mg,q12h×2d,第3天行依沙吖啶引产,对照组25例直接行依沙吖啶引产。结果:观察组平均引流产时间为(37.3±13.2)h,与对照组的(46.2±16.8)h比较,差异有统计学意义(P<0.05),产后刮出物量也低于对照组(P<0.05)。结论:米非司酮配伍依沙吖啶终止中期妊娠临床效果好,适宜临床广泛推广。
Objective: To investigate the clinical efficacy of mifepristone combined with ethacridine in induction of labor for the termination of second trimester pregnancy. Methods: The 65 women at 16-24 weeks' gestation requesting termination of second-trimester pregnancy were randomized into observation group and control group, who were treated by the hospital from October 2008 to May 2010. The 40 women of the observation group were taken 50 mg mifepristone every 12 hours for two days and followed by the induced labor with ethacridine in the third day, while the 25 women of the control group were directly treated induced labor with ethacridine. Results: The time of induced labor in observation group was (37.3±13.2) h, which was significantly shorter than that (46.2±16.8) h in the control group (P<0.05), the amount of tissue scratched out from the uterus were significantly lower in the observation group than ones in the control group ( P<0.05). Conclusion: Mifepristone combined with ethacridine in induction of labor is more effective than induced labor using ethacridine directly, and widely suitable for clinical applications.
出处
《中国当代医药》
2011年第33期68-69,共2页
China Modern Medicine
