摘要
目的:比较多索茶碱与氨茶碱治疗急性加重期慢性阻塞性肺疾病(AECOPD)的临床疗效。方法:将78例AE-COPD患者随机分为研究组和对照组,均进行常规治疗,研究组加用多索茶碱300mg,对照组加用氨茶碱250mg,1次/d,治疗周期均为7d,治疗结束后比较治疗效果。结果:治疗后,研究组患者临床症状体征改善情况显著优于对照组(P<0.05),两组患者肺功能指标改善情况差异有统计学意义(P<0.05)。结论:多索茶碱在控制AECOPD病情、改善患者肺功能方面优于氨茶碱,值得推广应用。
Objective: To compare the clinical efficacy of doxofylline and aminophylline in treating acute exacerbation chronic obstructive pulmonary disease (AECOPD). Methods: 78 patients of AECOPD were randomly divided into study group and control group. Besides from conventional therapy, the patients of the study group were treated with doxofylline 300 mg, while the control group were treated with aminophylline 250 mg once a day, the clinical efficacy were compared after 7 days. Results: After treatment, the clinical symptoms of the study group improved significantly better than the control group (P<0.05), there was a significant difference on lung function in two groups ( P<0.05). Conclusion: The clinical efficacy to improve lung function of doxofylline is superior to aminophylline in treating AECOPD, should be widely applied.
出处
《中国当代医药》
2011年第33期57-58,共2页
China Modern Medicine
关键词
多索茶碱
氨茶碱
急性加重期慢性阻塞性肺疾病
疗效比较
Doxofylline
Aminophylline
Acute exacerbation chronic obstructive pulmonary disease
Clinical efficacy
