摘要
[目的]观察900MHz电磁辐射对小鼠自发活动昼夜节律的影响。[方法]利用自发活动视频分析系统采集30只小鼠24h自发活动数据,绘制动物自发活动的昼夜节律拟合余弦曲线图,筛选出18只具有明显昼夜节律的小鼠,随机分为对照组、电磁辐射A组和电磁辐射B组。电磁辐射A组和电磁辐射B组小鼠分别在昼夜生理节奏时点(circadian time,CT)24:00点和12:00点接受40μW/cm2 900MHz电磁辐射,对照组不做任何处理,比较各组小鼠自发活动度昼夜节律的不同。[结果]与对照组相比,电磁辐射A组自发活动的昼夜节律曲线中值、振幅以及角频率差异有统计学意义;与对照组相比,电磁辐射B组各项指标的差异没有统计学意义。[结论]40μW/cm2 900MHz电磁辐射在CT0点照射能够影响小鼠自发活动度的昼夜节律,而在CT12点照射未对小鼠自发活动昼夜节律产生明显影响。
[Objective] To study the effect of 900 MHz electromagnetic radiation on circadian rhythm of spontaneous activity in mice.[Methods] The 24-hour spontaneous activities of 30 mice were measured,and the circadian rhythms of spontaneous activity were fitted to cosine curve.Eighteen mice with obvious circadian rhythm were randomly divided into three groups： control group,radiation group A and radiation group B.Mice in radiation group A and radiation group B were exposed to 40μW/cm2 900MHz electromagnetic radiation at circadian time（CT） 0 or 12 respectively.The data obtained from different groups were analyzed with cosine model and compared with each other.[Results] The parameters of cosine analysis showed statistical differences in median,amplitude and radian frequency between control group and group A,but,no obvious difference was observed between control group and group B.[Conclusion] The circadian rhythm of spontaneous activity in mice could be influenced by 40μW/cm2 900MHz electromagnetic radiation at CT0,but not at CT12.
出处
《环境与职业医学》
CAS
北大核心
2011年第11期680-683,共4页
Journal of Environmental and Occupational Medicine
基金
江苏省放射医学与防护重点实验室开放课题(编号:KJS0930)
关键词
电磁辐射
自发活动
昼夜节律
electromagnetic radiation
spontaneous activity
circadian rhythm
