摘要
目的观察急性颅脑损伤患者血清中C反应蛋白(CRP)和神经元特异性烯醇化酶(NSE)的表达特征,关注二者在颅脑损伤中的临床意义,以期为临床工作提供理论帮助。方法收集90例我院收治的急性颅脑损伤患者作为观察组,选取70例正常成人的血清标本作为对照组,检测两组血清中CRP和NSE的含量,分析二者在不同临床特征的意义及对预后判断的价值。结果急性颅脑损伤患者血清中CRP和NSE表达升高,重型颅脑损伤中的表达明显高于非重型颅脑损伤患者,死亡组患者的表达明显高于存活组,观察组患者血清中CRP和NSE的表达呈正相关。结论 CRP和NSE在急性颅脑损伤患者的血清中含量升高,联合检测血清中二者的含量对判断患者的病情程度及预后可能有重要价值。
Objective To study the expressions of CRP and NSE in patients with brain injury, investigate their relastionship and prognostic value. Methods The observation group included 90 cases of brain injury,the control group included 70 cases of normal adult serum. The expressions of CRP and NSE were detected in the two groups. We studied their clinical characteristic and prognostic value in brain injury. Results The expressions of CRP and NSE were higher in the observation group than in the control group. The expressions of CRP and NSE were correlated with severity and prognosis. The expressions of CRP and NSE were postive correlation in observation group. Conclusion The higher expressions of CRP and NSE can promote the ocurrence and development in patients with brain injury. The combined detection of CRP and NSE may be help to judge prognosis.
出处
《中国现代医生》
2011年第34期79-80,共2页
China Modern Doctor
