摘要
目的探讨振动反应成像(VRI)技术在慢性阻塞性肺疾病(COPD)患者中的应用价值。方法对255例COPD患者和78例健康志愿者行肺功能和VR I检查,分析VRI结果及其与肺功能的相关性。结果 COPD组的振动曲线评分3.07±1.34,动态图像评分7.81±3.27,振动值1.57±0.46,右肺肺部定量数据(QLD)值(49.5±12.6)%,啰音数5.27±7.74。对照组振动曲线评分1.14±1.00,动态图像评分2.24±1.27,振动值1.87±0.40,右肺QLD值(44.0±7.7)%,啰音数0.21±0.88。两组间以上指标均有显著差异(P<0.01)。COPD组VR I的振动曲线评分和动态图像评分与FEV1%pred呈线性相关(复合相关系数r=0.548,P<0.01),回归方程Y=80.833-2.735X1-5.406X2(Y:FEV1%pred,X1:动态图像评分,X2:振动曲线评分)。结论 COPD患者VRI结果与正常人存在显著差别,VRI对COPD的诊断、监测和病情进展评估具有重要价值。
Objective To explore the clinical value of vibration response imaging（VRI） in patients with chronic obstructive pulmonary disease（COPD）.Methods 255 COPD patients and 78 healthy volunteers were enrolled and lung function test and VRI examination were performed.The parameters of VRI included dynamic image grades,vibration energy graph grades,vibration value,quantitative lung data（QLD） of right lung,and crack counts.Results The VRI parameters of the COPD group were as follows,ie.dynamic image grades of 3.07±1.34,graph grades of 7.81±3.27,vibration value of 1.57±0.46,QLD of（49.5±12.6）%,crack counts of 5.27±7.74.The VRI parameters of the control group were as follows,ie.dynamic image grades of 1.14±1.00,graph grades of 2.24±1.27,vibration value of 1.87±0.40,QLD of（44.0±7.7）%,crack counts of 0.21±0.88.There were significant differences in all parameters between the two groups（all P0.05）.There was a linear relationship between VRI and FEV1%pred（r=0.548,P0.01）.The model of the linear regression was Y=80.833-2.735X1-5.406X2（Y：FEV1%pred,X1：VRI graph grades,X2：dynamic image grades）.Conclusion VRI is a promising method to diagnose and assess the severity of COPD.
出处
《中国呼吸与危重监护杂志》
CAS
2011年第1期25-29,共5页
Chinese Journal of Respiratory and Critical Care Medicine
基金
南京市卫生局科技发展计划(编号:YKK10103)
关键词
慢性阻塞性肺疾病
振动反应成像
肺功能
Chronic obstructive pulmonary disease
Vibration response imaging
Lung function
