摘要
目的:观察参麦注射液和丹参注射液对重度烧伤患者脓毒症中炎性细胞因子肿瘤坏死因子(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)水平的影响,探讨参麦注射液和丹参注射液在重度烧伤患者脓毒症治疗中的作用。方法:将60例重度烧伤致脓毒症患者随机分为两组:治疗组及对照组各30例。用放射免疫分析法检测治疗前、后炎性细胞因子肿瘤坏死因子(TNF-α)、白细胞介素-6(IL-6)、白细胞介素-8(IL-8)的水平。结果:治疗组TNF-α、IL-6、IL-8有显著下降。结论:参麦联合丹参注射液可显著降低炎性因子水平,从而保护多器官功能。
Objective：To observe the influence of Shenmai injection（SMI） and Danshen injection（DSI） on the serum levels of tumor necrosis factor-α（TNF-α）,interleukin-6（IL-6）,interleukin-8（IL-8） in sepsis patients with severe burn,and the protection action of SMI and DSI on sepsis patients with severe burn.Methods：60 cases of sepsis patients with severe burn were randomly divided into treatment group and control group,30 cases in each one.The serum levels of inflammatory cytokines（TNF-α,IL-6,IL-8）were measured with means of RIA before and after treatment.Results：The serum levels of TNF-α,IL-6,IL-8 in the treatment group decrease obviously.Conclusion：SMI and DSI can decrease apparently the serum levels of inflammatory cytokines,thus protect on multiple organs function.
出处
《医学理论与实践》
2011年第22期2665-2666,共2页
The Journal of Medical Theory and Practice
