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氨基末端脑钠肽前体与非ST段抬高急性冠状动脉综合征患者预后的相关性 被引量:2

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摘要 目的探讨非ST段抬高急性冠状动脉综合征患者氨基末端脑钠肽前体(NT-proBNP)水平与近期心功能和预后的关系。方法选择住院非ST段抬高急性冠状动脉综合征患者92例,分为非ST段抬高型心肌梗死(non-ST elevation myocardial infarction,NSTEMI)组和不稳定性心绞痛(unstable angina,UA)组,各46例,同时入选胸痛就诊但冠状动脉造影正常的患者46例作为对照组。所有患者入院后测定NT-proBNP浓度,分别于造影前及造影后3个月行超声心动检查。结果与对照组比较,NSTEMI组和UA组的NT-proBNP水平显著增高(P<0.05),左心室射血分数显著降低,差异有统计学意义(P<0.05)。NSTEMI组NT-proBNP明显高于UA组(P<0.05)。NT-proBNP水平与左心室射血分数呈负相关。结论 NT-proBNP可以预测非ST段抬高急性冠状动脉综合征患者的近期预后。
出处 《广东医学》 CAS CSCD 北大核心 2011年第18期2412-2413,共2页 Guangdong Medical Journal
基金 广东省惠州市科技计划项目(编号:2008Y058)
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参考文献6

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