摘要
目的:探讨我院药品不良反应(ADR)发生的特点及一般规律。方法:对我院2010年收集到的180例ADR报告按患者年龄、性别、给药途径、药品种类、ADR累涉及器官或系统及临床表现等进行分类统计与分析。结果:180例ADR报告中涉及的药品共有8大类,其中以抗微生物药引发的ADR比例最高(占35.00%),其次为中药及中药注射剂(占26.11%);静脉滴注比例较其他给药途径高(占82.22%);临床表现以皮肤及其附件损害比例最高(占37.78%),其次为全身性损害(占17.78%)。结论:临床应重视合理用药监测,积极上报ADR报告,避免或减少ADR的发生。
OBJECTIVE：To investigate the general rules and characteristics of the adverse drug reactions（ADR）in our hospital.METHODS：180 ADR reports collected from our hospital in 2010 were analyzed statistically in respects of age,sex,route of administration,drug type,organ or system involved in ADR and clinical manifestations.RESULTS：180 ADR reports involved a total of 8 major categories of drugs,with the highest proportion of antimicrobials（accounting for 35.00%）,followed by TCM and TCM injection（accounting for 26.11%）;the proportion of intravenous route of administration was more than others（accounting for 82.22%）;skin and its appendants damage accounted for the highest proportion of clinical manifestations（accounting for 37.78%）,followed by systemic damage（accounting for 17.78%）.CONCLUSION：Importance should be attached to rational drug use monitoring,reporting of ADR to avoid or minimize the occurrence of ADR cases.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第46期4398-4400,共3页
China Pharmacy
关键词
药品不良反应
监测报告
统计分析
Adverse drug reaction
Monitoring report
Statistical analysis
