摘要
Introduction 5-Monosubstituted isopropylidene malonates arc important synthetic organic intermediates. Since isopropylidene malonate has a stronger acidity （pK;=4.57）, its direct alkylation with alkyl halides usually gives 5,5-disubstitutcd isopropylidene malonates.
基金
Supported by the National Natural Science Foundation of China
the Basic Research Foundation of Zhejian Educational Commission.
