摘要
我们测定了35例血培养确诊的败血症患儿血清蛋白水平。结果表明其血清蛋白水平异常高达94.29%,绝大多数为降低.血清白蛋白与球蛋白同时降低或球蛋白下降者病死率和治疗无效的比例均显著高于对照组(P<0.01)。败血症并显性水肿者病死率与治疗无效比例也均显著高于无水肿组(P<0.05),水肿的原因主要是低蛋白血症。杆菌败血症组血清蛋白下降程度与发生率均比球菌组显著(P<0.05),杆菌组球蛋白值显著低于正常(P<0.05),而球菌组则不明显(P>0.1)。观察结果提示小儿败血症时急性蛋白质营养不良很常见,其发生与败血症的病原菌种类有关。测定血清蛋白水平对病情与预后的估计有帮助。
We determined the levels of serum protein in 35 children with septicemia diagnosed by blood culture,Ab- normal levels of serum protein were seen in 94.29% of the patients.In most eases,lowered levels were found. Mortality and inefficacy of the treatment were signifi cantly higher in patients with lower levels of both serum albumin and globulin or only serum globulin than in the control group (P< 0.01),and also significantly higher in patients with visible edema than those without edema (P< 0.05).Moreover,the main cause of visible edema was hypoproteinemia.Total serum protein was more greatly reduced in the bacillary septicemia group than in the coccal septicemia group (P< 0.05).Serum globulin was significantly lower in the bacillary group than nor- mal value (P<0.05).However,this phenomenon was not evident in the coccat septicemia group(P<0.1).we conclude that septicemia in small children is frequently complicated with protein malnutrition,the occurrence of which is related to the type of pathogenic bacteria.The determination of serum protein is helpful to the estimation of the condition and prognosis of the patients with sep- ticemia.
出处
《中国危重病急救医学》
CSCD
1991年第4期72-73,127,共3页
Chinese Critical Care Medicine
