摘要
本文测定了1987年9月～1989年9月我院产科门诊未曾服用钙剂及维生素 D,也无代谢性疾病或肾脏病的健康未产妇110人共113次,不同孕月的桡、尺骨骨矿含量,血钙、磷及25(OH)D_3和 AKP 的水平;尿钙及磷的排泄率。发现自第4孕月始骨矿面密度值、血钙水平及尿钙排泄率均有下降趋势;血磷水平有所下降,而尿磷排泄率增高;AKP随孕月有明显增高;25(OH)维生素 D_3处于正常范围。补充钙剂与维生素 D 可以阻断各项指标的变化。本文讨论了各项指标变化的意义并提出了预防措施。
Several indices including bone mineral content of radius and ulna (BMC and BMC/BW ),levels of serum calcium (Ca),phosphorus (P),alkaline phosphatase (AKP),25 (OH)D_3and urinary excretion rate of calcium (U-Ca/Cr) and phosphorus (U-P/Cr) were studied in 110healthy pregnant women without either metabolic or renal diseases.All subjects had not takencalcium and vit.D during the period from Sept.1987 to Sept.1989.BMC/BW,calcium levelsand U-Ca/Cr declined from the 4th pregnant month and maintained at the lower limit till fullterm.Levels of phosphorus also declined but U-P/Cr increased.AKP showed apparent increase,and levels of 25(OH)D_3 remained at normal range.Administration of calcium and Vit.D couldblock all changes mentioned above.The significance of the changes of these indices were discussedand the preventive measures proposed.
出处
《中日友好医院学报》
1991年第3期145-148,共4页
Journal of China-Japan Friendship Hospital
