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采用HBV-DNA探针对母婴HBV传播的临床研究 被引量:1

Clinical research about maternal-fetal transmission of hepatitis B virus by using probe of HBV-DNA
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摘要 本研究采用Dig-HBV-DNA探针检测了57例新生儿及其父、母血液、羊水、初乳和脐血6个标本及HBV标志物的检测、HBV-DNA检出率母血47.37%,父血42.11%,脐血40.35%,羊水7.02%,初乳22.81%,新生儿血为49.2%。14例抗-HBs阳性产妇,其自身HBV-DNA检出达42.86%,抗-HBs可通过胎盘传给新生儿,新生儿血中抗-HBs阳生率42.86%,HBV-NDA检出率为50%。同时亦观察了父母HBV感染对新生儿的影响,两者差异显著。 This paper detected 6 specimens of 57 cases including sera of neonatd and parent, am- notic fluid, earlg breasts and brood of umbilical coud with probe of Dig-HBV-DNA, also measure markes of hepatitis B virus, The analyse each other relation and contrast to two methods susceptible from individual sample postive rate, The result indications perinatal transmission of hepatitis B virus rate were higher, Althogh anti-HBs mag propagate placenta to newborn, neonatal HBV-DNA detection rate still 50 percewt, and it raises each specimens mesaure HBV-DNA t0 study clinical significance on maternal -fetal transmission of hepatitis B virus.
出处 《中国新生儿科杂志》 CAS 1993年第5期198-200,238-239,共5页 Chinese Journal of Neonatology
基金 浙江温岭科委立项科题
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  • 1刘培,董兆文.先天性人巨细胞病毒感染[J].中国优生与遗传杂志,1991(2):109-113. 被引量:7
  • 2董兆文,崔应琦,伦玉兰.利用孕早期人胚绒毛组织进行先天性巨细胞病毒感染诊断的研究[J],1992(02). 被引量:1
  • 3董兆文,陈岩,王毅,崔应琦.聚合酶链反应检测人早孕绒毛组织中巨细胞病毒感染[J]生殖医学杂志,1992(01). 被引量:2
  • 4严仁英.实用优生学[M]人民卫生出版社,1986. 被引量:1
  • 5Hillis,SD,Nakashima,A,Marohbanks,PA,et al.Risk factors for recurrent Chlamydia trachomatis infections in women. American Journal of Obstetrics and Gynecology . 1994 被引量:1
  • 6Pao,CC,Yao Ding-shyan,Lin Chieh-Yu,et al.Prenatal transmission of hepatitis B virus to neonates born to serum bepatitis B Virus DNA-positive mothers. The American Journal of Perinatology . 1992 被引量:1
  • 7张淑润.人类微小病毒B_(19)与胎儿[J].北京医学,1991,13(4):228-230. 被引量:2

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