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早产儿动脉导管未闭(附10例临床分析)

PATENT DUCTUS ARTERIOUS IN 10 PREMATURE INFANT
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摘要 本文报告10例早产儿动脉导管未闭(PDA)。发生PDA因素为严重室息、肺炎、RDS及胎粪吸入综合征。8例在胸骨左缘第1~2或2~3肋间听到2/6~3/6级收缩期杂音,2例为连续性杂音。4例合并心力衰竭。8例经二维超声心动图和多普勒频谱分析其中7例证实有PDA。9例口服消炎痛治疗,有效率为77%。1例自然关闭。4例用地高辛治疗心力衰竭。无不良反应。 This paper reports patent ductus arteriosus in 10 premature infants, whose gestational age are<37 weeks. The related factors recurring PDA are severe asphyxia, RDS, pneumonia and meconium aspiration. A 2/6-3/6 grade heart murmur was heard at the left stermal border in the second or third intercostal space in 8 infants. Two were continuous murmur. Four infants developed heart failure. Chest x-ray CTR>0.6 in them. M-mode echocardiogram showed LA/AO>1.2 in four infants. The ductus arteriosus was insulized directly by 2DE- echocardiography and Doppler in seven infants. Nine infants were treatet by oral indomethacin. They all recei- ved treatment 1-28 days after birth. Among them six were treated less than seven days; two of nine infants, treated by indomethacin 13 days after birth and 32 days later for the second time. Seven infants' heart murmur disappeared after treatment for 0.5-7 days (mean 2.3 days). Ductus arteriosus spontaneous closed was only one infant. Heart failure of four infants was treated with digoxin.
出处 《中国新生儿科杂志》 CAS 1993年第3期104-106,143,共4页 Chinese Journal of Neonatology
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