摘要
应用放射免疫方法测定１６６例接受胃镜检查者的胃窦部粘膜的生长抑素（ＳＳ）含量，比较几种胃、十二指肠疾病患者与正常人的差异，并探讨胃窦粘膜ＳＳ含量与胃窦部病理改变及幽门螺杆菌（ＨＰ）感染之间的关系。结果显示：胃溃疡、慢性萎缩性胃炎、胃癌患者胃窦部粘膜ＳＳ含量明显低于正常对照组；胃窦部粘膜出现肠上皮化生和不典型增生改变者ＳＳ含量明显低于不伴这些改变者；ＳＳ含量与ＨＰ感染关系不明显。
We investigated the effects of gastroduodenal diseases,Helicobacter pylori (HP)infection on somatostatin(SS)concentration of gastric antral mucosa.SS concentration was measured by radioimmunoassay in 166 cases undergone the usual endoscopy procedure.The results showed that the SS contents of antral mucosa were reduced significantly in the patients with gastric ulcer,chronic atrophic gastritis,gastric cancer and chronic gastritis accompanied by atypical hyperplasia,intestinal metaplasia.HP infection did not effect markedly on SS concentration of antral mucosa. It is suggested that gastric mucosa atrophic change,atypical hyperplasia and intestinal metaplasia may reduce SS concentration of the antral mucosa and relate to the development of gastric cancer.
出处
《福建医科大学学报》
1994年第4期362-364,共3页
Journal of Fujian Medical University
关键词
生长抑素
慢性胃炎
胃癌
幽门螺杆菌
somatostatin chronic gastritis gastric cancer Helicobacter pylori
