摘要
对照观察60例高血压患者和24例正常人血液流变学。结果显示35例患者（58．3％）血液流变学异常，表现为全血粘度、血浆粘度、红细胞聚集指数和红细胞压积增高、红细胞电泳时间延长；另25例患者（41．7％）血液流变学正常。卡托普利降压治疗后显效29例（48．3％），有效13例（21．6％），总有效率70％。卡托普利维持有效降压治疗113±11（3～4月）后，血液流变学异常患者各项指标均明显改善，对血液流变学正常患者则无影响。
Sixty petients with hypertension and 24 nomotensivesubjects underwent hemorrheological study and the effect of 3 - 4months captoptil treatment was evaluated. The results showed that 35petients (58. 3%) had an incrcased relative bled viscosity at higher(RBVH) nd lower shear rates (RBVL) and relative plasma visoosity(RPV), higher red-cell aggregation index (RAI) and hematocrite(Hct), the longer erythrocyte electrophoresis time (EET), while theother 25 petients (41. 7%) had a normal hemorrneologic states. af-ter captopril therapy for 113± 11 days (3- 4 months), a satisfiedantihypertensive effect was achieved in 42 petients (70%). Thehemorrhedlogic states were improved significantly in the petients withPretreatment abnormal RBVH, RBVL, RPV, RAI and Hct, andlonger EET, and no change being found in those with pretreatment normal hemorrheologic states. It is concluded that captopril has a sat-isfaotory antihypertensive effects and improves the abnormal hemor-rheologic states.
出处
《中华高血压杂志》
CAS
CSCD
1994年第3期177-179,共3页
Chinese Journal of Hypertension
