摘要
Promoted by stannous salts, 1,1,1-trichloro-2,2,2-trifluoroethane reacts readily with aliphatic, aromatic, and α, β-unsaturated aldehydes giving the corresponding alcohols bearing a CF3CCl2-moiety in good to excellent yields. These alcohols are farther oxidized by Jones reagent giving the corresponding ketones in high yields.
Promoted by stannous salts, 1,1,1-trichloro-2,2,2-trifluoroethane reacts readily with aliphatic, aromatic, and α, β-unsaturated aldehydes giving the corresponding alcohols bearing a CF3CCl2-moiety in good to excellent yields. These alcohols are farther oxidized by Jones reagent giving the corresponding ketones in high yields.
基金
Project supported by the National Natural Science Foundation of China.
