摘要
分别用ＤＭＰＡ与丹那唑治疗子宫内膜异位症各１６例。用ＤＭＰＡ后ＦＳＨ、ＬＨ、Ｅ２、Ｔ均被抑制；用丹那唑后ＦＳＨ、ＬＨ被抑制，但Ｅ２与Ｔ上升。临床上两组均抑制排卯及有雌激素低效应，缓解症状满意，体征有一定的改善。一个疗程后ＤＭＰＡ组闭经比丹那唑组少，而不规则出血则多于丹那唑组；在增加体重、对肝功影响及一般不适上ＤＭＰＡ组好于丹那唑组。临床上两药相比由于ＤＭＰＡ使用简便，副反应轻，可连续多次应用，更受患者欢迎。
The DMPA treatment of endometriosis were compared with Danazol treatment in each 16 cases.In DMPA group FSH, LH, E_2, T levels were significantly decreased after 3 months treatment .Danazol group FSH, LH were also significantly decreased, but E_2,T were significantly increased correlatively. In both groups estrogen levels were suppressed in vaginal smears, BBT were monophasic.After 3 months treatment dysmenorrhea were all relieved in both groups. The therapeutic effects were 11/16 in DMPA group and 7/12 in Danazol group under ultrasonic and pelvic examination.Amenorrhea appeared 3/16 in DMPA group, 4/14 in Danazol group; irregular bleedings were 13/16 in DMPA group, 3/14 in Danazol group. Average body weight increased in DMPA group was 1.9kg, and that in Danazol group was 2.6kg. Disturbed liver function was 1/16 in DMPA group, and 5/16 in Danazol group.There was no androgenic effect in DMPA group. In DWA group menses recurred 3 months to 1 year after treatment , showing its cumulative action. We conclude that DMPA is a simple method with slight adverse effect which patient prefers to use.
出处
《现代妇产科进展》
CSCD
1994年第2期122-124,195,共4页
Progress in Obstetrics and Gynecology
关键词
醋酸甲孕酮
丹那唑
子宫内膜异位
Depo-Medroxy-progesterone Acetate
Danazol
Endometriosis
