摘要
食醋灌胃 SD 大鼠,造成脾气虚证动物模型,用人参、黄芪、党参、白术、山药、大枣治疗。结果:各药均能改善脾虚症状,增加摄食量及自发活动,大便恢复正常,消除腹胀、胃肠炎变,增加胃肠粘液,升高血清 D-木糖,增加小肠粘膜表面微绒毛、肠上皮细胞线粒体;但六药各具特点,人参补脾作用明显,提高免疫功能最优;党参功同人参而力弱,又能升高血清淀粉酶;黄芪作用不及人参、白术,但有升高血清蛋白及血细胞的趋势;白术补脾作用明显,又能升高血清总蛋白;山药补脾功同人参、白术,又能明显增加胃肠粘液;大枣补脾力弱。
Vinegar were fed into the stomach of SD rats.the model of Spleen Qi Deficiency (SQD) was set up.Then treated with Panax ginseng,Astragalus membranaceus.Codonopsis pilosula,Atractylodes macrocephala. Dioscorea opposita and Ziziphus jujuba.The results showed that they all could improve the symptom of SQD. such as increas ingestion,eliminating abdominal distention,resuming normal stool,increasing spontaneous activ- ity,eliminating gastrointestinal inflammatory lesion,increasing gastrointestinal mucus,elevating serum D-Xy- lose,increasing microvilli of intestinal mucous membrane and mitochondria of intestinal epithelial cells.Above- mentioned improvement were different in SQD rats.But,their effect on strengthening Spleen had various distin- guished features.Panax ginseng was outstanding in strengthening Spleen.and served best of elevating the immu- nizing effect.The effect of Codonopsis pilosula was similar to Panax ginseng but weaken in effect,it could raise the serum amylase.Astragalus membranaceus was not so good as Panax ginseng,but it had the trend of increas- ing serum albumin and blood cells.Astractylodes macroccphala had the effect of strengthening Spleen.it could in- crease serum albumin,Dioscorea opposita was obvious in strengthening Spleen,its efficacy was as good as Panax ginseng and Atractylodes macrocephala,it could increase the gastrointestinal mucus.Ziziphus jujuba was weak in strengthening Spleen.
出处
《中国中西医结合杂志》
CAS
CSCD
北大核心
1995年第S1期302-304,403-404,共5页
Chinese Journal of Integrated Traditional and Western Medicine
关键词
补气药
脾气虚证动物模型
药理学研究
Medicine of strengthening Qi
animal model
symptomatology
hematology
morphology
immunology
comparative study
