摘要
目的：观察烧伤休克延迟复苏后内脏能量代谢的变化．方法：通过建立大鼠烧伤休克延迟复苏模型，测定烧伤后不复苏、立即复苏和延迟复苏后心、肺、肝、肾中ＡＴＰ含量及肺、肾组织Ｎａ＋，Ｋ＋－ＡＴＰ酶活力的变化。结果：实验发现烧伤后３种复苏条件下都有ＡＴＰ含量的一过性上升，随后下降。肺、肾ＡＴＰ酶活力在伤后３０ｍｉｎ即已开始下降，在１２ｈ和６ｈ分别降至最低点，随后逐渐回升。结论：烧伤早期内脏中能量代谢紊乱是明显的，其中不仅有能量供应障碍，而且还有能量利用障碍。
Objective: We tested the content of ATP in the heart,lung,liver and kidney and the activity of ATPase in the lung and kidney of rats sustaining delayed resuscitation of burn shock to investigate the changes of energy metabolism in viscera.Methods:Using the fluoresence method,we measured the content of ATP in viscera and according to Chapman's method,we tested the activity of ATPase in the lung and kidney.Results:ATP contents in viscera increased at the beginning and decreased later. The ATPase activity in the lung and kidney decreased significanly.Conclusion: Energy disturbance appears in burn and delayed resuscitation,which includes not only energy supply but also energy application.
出处
《第二军医大学学报》
CAS
CSCD
北大核心
1996年第S1期25-27,共3页
Academic Journal of Second Military Medical University
基金
国家自然科学基金
