摘要
AIM To evaluate the diagnostic value of fecal occult blood testing in mass screening for colorectal cancer. METHODS The reversed passive hemagglutination reaction fecal occult blood testing (RPHA FOBT) and colorectal cancer′s risk factor quantitative method as the preliminary screening, and 60 cm fiberoptic colonoscopy as the accurate screening were used to detect colorectal cancer in a natural community of 75813 subjects in this study. RESULTS As compared with the 60cm fiberoptic colonoscopy as a standard reference, FOBT has a sensitivity of 41 9%, specificity of 95 8%, Youden′s index 0 38, and positive predictive value of 0 68%, these results went up with age in the subjects from the first detection. A 3 year follow up in the target mass showed that all new cases were once FOBT negative. CONCLUSION Values in FOBT as an indicator of mass screening for colorectal cancer were limited.
