摘要
回顾性总结了我院十年中具有较完整资料的新生儿TPN106例。TPN均完成5天以上，其中治愈96例，死亡9例，放弃1例。体重增加63例，不变36例，下降7例，平均体重增加16克／天。发生并发症24例（23％），好发于TPN＞2周的早产儿，以胆汁瘀积和肝损害、高脂血症、贫血、低磷、低钙为常见。建议新生儿TPN时应遵循下列常规：（1）热卡摄入60～80Kcal·kg－1·d－1。（2）液体一般情况下120～160ml·kg－1·d－1。（3）氨基酸选用小儿专用配方，剂量为2～3g·kg－1·d－1。（4）脂肪乳剂为1～3g·kg－1·d－1，一天量应滴注＞16小时，早产儿、有黄疸或肝功能异常者可选用含MCT的脂肪乳剂。（5）葡萄糖开始剂量8～10mg·kg－1·min－1，如耐受良好，可逐渐增加。（6）钙、磷、铁元素应常规每天给予。（7）尽早少量口服喂养。这样并发症可望下降到10％以下。
TPN in neonates is a new useful and sophisticated technique. Since May 1985, our hos-pital has first implemented it in our nation. To the end of 1995, 106 neonates accepted TPN over 5 days in our hospital. Among them, 96 children recovered, 9 cases died and 1 patient suspended trearment and went home. Weight was gained in 63 neonates, lost in 7 cases and kept in 36 cases, the average increase of body weight was 16g/d. 24 patients (23%) had different TPN-related complications, cholestasis,liver damage, hyperlipemia, anemia, hypophosphatemia, hypocalcemia listed as common ones, they of-ten occured in prematures with TPN over 2 weeks. In conclusion, by review of our own experience and TPN-related references, we suggest in neonatal TPN (1) Energy: 60～80Kcal/kg·d (2)Volume of liq-uid: 120～160ml/kg·d (3) Amino acid solution: children specific solution should be the first seletion,with 2～3/kg·d (4) Fat emulsion: 1～3g/kg·d, the dosage of one-day should be administered intra-venously over 16 hours. Prematures, patients with jaundice or abnormal liver function should accept the MCT-containing solutions (5) Glucose: 8～10mg/kg·min (6) Calcium, phosphorus and iron should be given daily (7) Oral feeding shoule begin as early as possible when permitted.
出处
《中华临床营养杂志》
CAS
1998年第1期11-15,共5页
Chinese Journal of Clinical Nutrition
关键词
新生儿
静脉营养
Newborn Parenteral-nutrition
