摘要
A rapid and sensitive 1.5 order adsorptive stripping voltammetric method fordetendnation of trace mitoxantrone (MXT) is described. The accumulation behavior of MXT on amercury film ndcroelectrode was studied and the possibility of carrying out 1.5 order differentialadsorptive stripping analysis using mercury-coated carbon fiber ndcroelectrode was demonstrated.Optimal conditions for 1.5 order differential voltammetry monitoring are described. The strippingpeak current is linearly proportional to the concentration of MAT in the range of 1.0×10-6 mol/L 1.0×10-9 and detection licit is 1.5×10-10 mol/L. The relative standard deviation (RSD) is 3.0% at5.0×10-8 (n=8). MXT can be detendned directly in biological samples at physiological levelswithout any separation procedure.
A rapid and sensitive 1.5 order adsorptive stripping voltammetric method fordetendnation of trace mitoxantrone (MXT) is described. The accumulation behavior of MXT on amercury film ndcroelectrode was studied and the possibility of carrying out 1.5 order differentialadsorptive stripping analysis using mercury-coated carbon fiber ndcroelectrode was demonstrated.Optimal conditions for 1.5 order differential voltammetry monitoring are described. The strippingpeak current is linearly proportional to the concentration of MAT in the range of 1.0×10-6 mol/L 1.0×10-9 and detection licit is 1.5×10-10 mol/L. The relative standard deviation (RSD) is 3.0% at5.0×10-8 (n=8). MXT can be detendned directly in biological samples at physiological levelswithout any separation procedure.
