摘要
目的:观察奥美拉唑与阿莫西林、呋喃唑酮、胶态果胶铋剂四联治疗上消化道溃疡的疗效.方法:采用随机分组平行对照法,全组共100例,对照组用奥美拉唑20mg/d,共4wk;治疗组(四联疗法)采用奥美拉唑20mg/d,阿莫西林500mg tid,呋喃唑酮200mg tid,胶态果胶铋剂100mg tid,共2wk.结果:溃疡痊愈率治疗组为100%,对照组为92.0%(P>0.05)IIP根除率治疗组为93.88%,对照组为28.57%(P<O.01).腹痛缓解时间治疗组短.治疗中未见明显不良反应.结论:治疗组IIP根除率明显优于对照组,溃疡愈合率两种疗法相似.
AIM: To investigate clinical curative effects of omeorazole, amoxicillin, fura-zolidone, colloid pectin biagent in the treatment of 100 patients with duodenum ulcer(DU) and gastric ulcer(GU)by the method of parallel control in random groups. METHODS:In the control groups (omeprazole 20 mg/d),the course of treatment was 4 wk,in the treatment groups omeprazole 20 mg/d ,amoxicillin 500 mg tid .furazolidone 200 mg tid,colloid pectin bi-agent 100 mg tid )the course of treatment was 2 wk. RESULTS:The healing rate of DU and GU was 100% in the treatment groups and 92. 0% in the control groups(P>0. 05 ). Eradica-tion rate of HP was 93. 88% in the treatment groups and 28. 57% in the control groups(p< 0. 01). Obvious adverse reaction was not found in the treatment. The ventral gastralgia catabasis in the treatment group was shorter than that of control. CONCLUSION: Eradica-tion rate of HP are better in the treatment group than in the control groups. Two therapy of the healing rate of DU and GU are similar.
出处
《中国临床药学杂志》
CAS
1999年第S1期3-5,共3页
Chinese Journal of Clinical Pharmacy
关键词
奥美拉唑
阿莫西林
呋喃唑酮
胶态果胶铋剂
胃十二指肠溃疡
疗效
omeprazole
amoxicillin
furazolidon
colloid pectin biagcnt
duodenum ulcer and gastric ulcer
curative effect
