摘要
目的分析儿童肌阵挛性癫痫的临床特点与疗效。方法回顾性分析山西省昔阳县人民医院1990-2005年诊治35例儿童肌阵挛性癫痫的临床资料,对其临床特点与治疗效果进行分析。结果7例(20%)患儿有癫痫家族史,11例(31.4%)有高热惊厥史。睡眠及闪光诱发脑电图检查可提高癫痫的检出率。6例治疗中出现病情加重倾向,2例重症肌阵挛性癫痫死亡,应用丙戊酸钠单药治疗28例(80%)效果满意。结论儿童肌阵挛性癫痫易误诊误治,小剂量丙戊酸钠治疗效果好。重症儿童肌阵挛性癫痫预后差,病死率高。
Objective To analyze the clinical characteristics and curative effects of myoclonic epilepsy in children. Methods 35 cases were used to retrospectively study to analyze the medical history、clinical features and treatments.Results 7 patients(20%) had a family history of epilepsy while 11 cases(31.4%) had a history of febrile convulsion.The first onset was about at the age of 8.0±2.4. The first onset of myoclonic seizure and generalized tonic-clonic seizure would be put off and the diagnostic time would be delayed by 3.4 years.EEG induced by sleep and/or flash could raise the epileptic detectable rate.6 children had a tendency to be aggravated during the treatment.2 cases died of severe myoclonic epilepsy.28 patients(80%) were treated only by sodium vedproate and the effects were satisfying.Conclusion It is easily wrongly diagnosed and treated. Taking small dose of sodium vedproate drugs,the patients have better treatment effects.The children with severe myoclonic epilepsy have poor prognosis and high death rate.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2008年第S2期65-66,共2页
Chinese Journal of Practical Internal Medicine
