摘要
目的了解抗菌药不良反应发生情况,为临床合理用药提供参考。方法应用分类统计和分析评价法,对我校附属医院2009—2010年抗菌药引起的109例不良反应报告进行统计分析。结果 109例病人中,女性多于男性,46~60岁年龄段构成比最高,占46.79%;共涉及30种抗菌药,以β-内酰胺类抗菌药（包括青霉素类和头孢菌素类）引发的不良反应最多（52例,占47.71%）;给药途径以静脉给药为主,占93.58%;临床表现以皮肤和消化系统损害为主,分别占32.11%和24.77%。结论抗菌药不良反应日渐增多,应充分重视不良反应的监测,合理使用抗菌药物。
Objective To understand the adverse drug reactions due to antiseptics and provide a reference for their reasonable use.Methods Using classification and statistics and analytic evaluation,109 cases with adverse effects caused by antibiotics seen in our affiliated hospital（during 2009—2010） were analyzed.Results Of the 109 cases reported,more were women.The highest ratio was seen in those of 46-60-year-old,accounting for 46.79%.Thirty kinds of antiseptics were involved,of which,β-lactams,including penicillins and cephalosporins,caused the majority of the cases（52,accounted for 47.71%）.The side effects were mainly seen in intravenous medication（93.58%）;clinically,skin and digestive system impairment were mainly involved,32.11% and 24.77%,respectively.Conclusion Adverse drug reactions of antiseptics are increasing day by day.A monitoring of these side effects should be fully oriented,and the drugs be used accurately.
出处
《齐鲁医学杂志》
2011年第6期506-507,509,共3页
Medical Journal of Qilu
关键词
不良反应
抗菌药
数据收集
adverse reaction
anti-bacterial agents
data collection
