摘要
目的探讨早产儿重度脑室周围-脑室内出血的高危因素。方法选择2008—2009年我院新生儿重症监护病房重度脑室周围-脑室内出血的早产儿为观察组,同期轻度脑室周围-脑室内出血早产儿为对照组,对引起早产儿脑室周围-脑室内出血可能的15项临床因素进行统计学分析。结果观察组32例,死亡6例,放弃治疗12例;对照组93例,死亡1例,放弃治疗2例。单因素分析显示,胎龄、出生体重、前置胎盘、产时窒息、宫内窘迫、低氧血症、高碳酸血症、机械通气、吸入高浓度氧等与早产儿重度脑室周围-脑室内出血有关(P均<0.05)。多因素Logistic回归分析显示,胎龄(OR=3.545)、出生体重(OR=3.453)、产时窒息(OR=3.232)、机械通气(OR=3.643)和吸入高浓度氧(OR=3.449)为早产儿重度脑室周围-脑室内出血的高危因素(P均<0.05)。结论早产儿脑室周围-脑室内出血的高危因素较多,而且预后差,早期预防早产儿重度脑室周围-脑室内出血并采取积极干预措施具有重要意义。
Objective To study the risk factors and provide the clinical evidence in prophylaxis and treatment for severe periventricular hemorrhage-intraventricular hemorrhage in preterm infants.Methods From our NICU database,we chosed chose,32 severe periventricular hemorrhage-intraventricular hemorrhage cases for experimental group,6 cases died,12 cases treatment abandoned;93 cases of mild periventricul-ar hemorrhage-intraventricular hemorrhage for control group in the mean time,for 1 case dead,2 case given up.Analysis the 14 factors leading to periventricular hemorrhage-intraventricular hemorrhage in preterm birth statisticcally.Results Several significant risk factors for severe periventricular hemorrhage-intraventricular hemorrhage were gestational age,birth weight,placenta previa,asphysia,hypoxemia,hypercapnia,mechanical ventilatiom,inhalation of high concentration oxygen （P0.01）.Identified these factors by logistic regression analysis such as gestational age （OR=3.545）,birth weight （OR=3.453）,asphysia （OR=3.232）,mechanical ventilatiom （OR=3.643）,inhalation of concentration （OR=3.449） were statistically significant （P0.05）.Conclusions There are a lot of high risk factors for periventricular hemorrhage-intraventricular hemorrhage in preterm baby.We should emphasised on the severe periventricular hemorrhage-intraventricular hemorrhage in the treatment of the preterm baby because of its poor prognosis,that will improve the predictability of this disease and give the positive intervention as early as possible.
出处
《中国新生儿科杂志》
CAS
2011年第6期386-388,共3页
Chinese Journal of Neonatology
关键词
颅内出血
危险因素
婴儿
早产
Intracranial hemorrhages
Risk factors
Infant
premature
