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Betaine and nonalcoholic steatohepatitis: Back to the future? 被引量：7

Betaine and nonalcoholic steatohepatitis: Back to the future?
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摘要 Nonalcoholic steatohepatitis (NASH) is an important indication for liver transplantation in many Western countries. Obesity and insulin resistance are the two most common risk factors for NASH, which can lead to recurrent NASH after liver transplantation. There is currently no approved therapy for NASH, and treatment is directed at risk factor modification and lifestyle changes. Betaine has been used for NASH, with mixed results, and may show promise in conjunction with other agents in clinical trials. Nonalcoholic steatohepatitis （NASH） is an important indication for liver transplantation in many Western countries. Obesity and insulin resistance are the two most common risk factors for NASH, which can lead to recurrent NASH after liver transplantation. There is currently no approved therapy for NASH, and treatment is directed at risk factor modification and lifestyle changes. Betaine has been used for NASH, with mixed results, and may show promise in conjunction with other agents in clinical trials.
作者 Sandeep Mukherjee
机构地区 Section of Gastroenterology and Hepatology
出处 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第32期3663-3664,共2页 世界胃肠病学杂志（英文版）
关键词 BETAINE Nonalcoholic steatohepatitis CIRRHOSIS OBESITY Insulin resistance 酒精性 甜菜碱 肝炎 脂肪 胰岛素抵抗 西方国家 NASH 危险因素
分类号 R575.5 [医药卫生—消化系统]
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参考文献11

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World Journal of Gastroenterology
2011年 第32期

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