摘要
目的评估阿立哌唑治疗精神分裂症的疗效和副反应。方法将93例首发精神分裂症住院患者随机均分为两组，分别给予阿立哌唑和利培酮治疗8周。采用阳性症状与阴性症状量表（PANSS）和副反应量表（TESS）评定疗效与副反应。结果两组疗效和副反应发生率比较无显著性差异，但阿立哌唑的锥体外系反应和内分泌改变发生率显著低-I-~,J培酮。结论阿盘哌唑治疗精神分裂症安全有效。
Objective To estimate the efficacy and side effects of aripiprazole in the treatment of schizophrenia. Methods Ninty-three inpatients with schizophrenia were randomly allocated to two groups treated with aripiprazole or fisperidone respectively for 8 weeks[ The Positive and Negative Syndrome Scale （PANSS） and Treatment Emergent Side Effect Scale （TESS） were used to evaluate the efficacy and side effects. Results The clinical efficacy and the incidence of side effects in the two groups had no significant difference, but the incidence of extrapyramidal symptoms and endocriniic change in the aripiprazole group was significantly lower than that in rineridone group Conclusion AriDit）razle is safe and effective in treating schizophrenia.
作者
田爽
张立杰
TIAN Shuang, ZHANG Li-jie （Rizhao Mental Health Center of Shandong Province, Rizhao 276800,China）
出处
《医学信息》
2011年第21期88-89,共2页
Journal of Medical Information
