摘要
目的对81例反复呼吸道感染(RRI)患儿的免疫功能进行总结分析,研究RRI患儿的免疫功能。方法以81例RRI患儿为研究对象,检测CD3+、CD4+、CD8+,计算CD4+/CD8+比值;测定IgA、IgG、IgM;并与72例正常健康儿童进行比较。结果 RRI患儿的CD3+、CD4+/CD8+比值明显降低,CD8+明显升高,差异有统计学意义(P<0.05);血清IgM、IgG显著高于健康儿童,补体C3明显降低,差异有统计学意义(P<0.05),IgA无显性变化。结论患儿RRI与免疫功能紊乱有关。
OBJECTIVE To summarize the immune functions of 81 cases of children with recurrent respiratory tract infection（RRI）. METHODS A total of 81 cases of clinically diagnosed children with recurrent respiratory tract infections were set as study object, whose CD3＋ , CD4＋ , CD8＋ were tested and, calculated CD4＋/CD8＋ ratio. The level of IgA, IgG, IgM; and with 72 normal healthy children were compared. RESULTS RRI children CD3 ＋ , CD4＋/CD8＋ ratio decreased, CD8＋ was significantly higher （P〈0.05）, significant difference; serum IgM, IgG was significantly higher than healthy children, C3 significantly lower （P〈0.05）, there was no significant change of IgA. CONCLUSION Children with recurrent respiratory tract infections are related to immune function disorders.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第21期4492-4493,共2页
Chinese Journal of Nosocomiology
关键词
反复呼吸道感染
儿童
免疫功能
Recurrent respiratory tract infection
Children
Immune infection
