摘要
以香草醛和丙二酸为原料,乙酸铵为催化剂,合成阿魏酸。考察反应时间、投料物质的量比、催化剂用量和溶剂体积比等因素对收率的影响。结果表明,N,N-二甲基甲酰胺作溶剂,环己烷作带水剂,在V(环己烷):V(N,N-二甲基甲酰胺)=2:1、催化剂用量占香草醛质量的6%、n(香草醛):n(丙二酸)=1:1.3和反应时间4 h条件下,阿魏酸收率为70.87%。
Ferulic acid was synthesized by using vanillic aldehyde and malonic acid as raw materials, and ammonium acetate as the catalyst. The influence of reaction time, molar ratio of reactants, catalyst dosage and volume ratio of cyclohexane to N, N-dimethylformamide （DMF） on ferulic acid yield was investigated. The experimental results indicated that ferulic acid yield of 70.87% was attained under the optimum reaction condition as follows：DMF as the solvent, cyclohexane as the water carrying agent, volume ratio of cyclohexane to DMF = 2 ： 1, catalyst dosage 6% of mass of vanillic aldehyde, molar ratio of vanillic aldehyde to malonie acid 1： 1.3, and reaction time 4 h.
出处
《工业催化》
CAS
2011年第10期70-72,共3页
Industrial Catalysis
