摘要
精原细胞包括未分化型精原细胞和分化型精原细胞。通过体外培养精原细胞,重现精子发生过程,在发育生物学、生命起源和生育控制等领域具有重要意义;通过精原干细胞的体外培养,利用其多能性,诱导其产生多种组织类型的细胞,将是再生医学研究领域的热点,本文拟就精原细胞体外培养的影响因素作一综述,旨在为精原细胞体外培养体系的建立提供借鉴。
Spermatogonia include undifferentiated spermatogonial cell and differentiated spermatogonial cell. It is very important to reappear spermatogenesis by isolation and in vitro culture of spermatogonial stem cells in aspect of developmental biology, origin of life and birth control. It will be a hotspot in regenerative medicine that spermatogonial stem cells are cultured in vitro to induce a variety of tissue type cells utilizing their pluripotency. This review introduces some influential factors of spermatogonial stem cells cultured in vitro. It may provide the theoretical assistance for the spermatogonial stem cells cultured in vitro.
出处
《生殖医学杂志》
CAS
2011年第5期430-434,共5页
Journal of Reproductive Medicine
基金
贵州省优秀青年科技人才培养对象基金黔科合人字(2009)26号
遵义市重大科技项目培育与科技人才培养计划遵科培字2009(20)号
关键词
精原细胞
体外培养
干细胞
Spermatogonial cells
Culture in vitro
Stem cells
