摘要
目的:探讨颅脑损伤后低钠血症的治疗。方法:回顾性分析238例颅脑损伤患者,根据治疗方式的不同分为早期补充浓氯化钠组和常规补液组,早期补浓氯化钠组107例采取电解质钠离子低于135 mmol/L时予3%浓氯化钠500 ml/d治疗,对照组131例采取常规补充生理需要量治疗,治疗后统计分析2组之间治疗结果差异。结果:早期补浓氯化钠组低钠血症纠正率明显高于对照组。结论:颅脑损伤患者当一旦出现低钠血症,立即予浓氯化钠治疗,能明显快速纠正低钠血症,且不会增加抗利尿激素异常分泌综合征(Syndrome of inappropriate antidiuretic hormone,SIADH)的发生率。
Objective：To discuss the treatment and clinical characteristics of hyponatremia after brain trauma.Methods：238 patients with complicated hyponatremia after brain injury were enrolled in this retrospective study.According to treatment,all patients were divided into two groups：hypertonic saline solution injecting group（HSSI group） and control group.500 ml of 3% sodium chloride was injected per-day in 107 patients of HSSI group when serum sodium were lower than 135 mmol/L,and routine fluid infusion according to physiological requirement was performed in 131 patients of control group.Recovery rate and recurrence of hyponatremia were measured to be compared between two groups.Results：Recovery rate of serum sodium in HSSI group was significantly higher than that in control group.Conclusion：HSSI had a significant therapeutic effect on patients with complicated hyponatremia after traumatic brain injury;moreover,it did not increase the incidence of SIADH.
出处
《重庆医科大学学报》
CAS
CSCD
北大核心
2011年第9期1138-1140,共3页
Journal of Chongqing Medical University
