期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

FOXM1在结直肠腺瘤和结直肠癌组织中的异常表达及意义 被引量：4

下载PDF
导出
摘要 引言细胞周期紊乱是肿瘤最主要的发生机制[1]。叉头框M1（Forkhead box M1,FOXM1）基因在细胞周期调控中起着重要作用,其表达水平的细微变化都能导致细胞增殖能力的改变,因此其表达水平的精确调控对有丝分裂和细胞增殖的正常进行至关重要[2]。正常情况下。
作者 唐慧 郭强 朱军 张超 李丽 严新民
机构地区 云南省第一人民医院临床基础医学研究所 昆明医学院附属昆华医院临床基础医学研究所 云南省第一人民医院消化内科 云南省第一人民医院普外Ⅱ科
出处 《肿瘤防治研究》 CAS CSCD 北大核心 2011年第10期1197-1200,共4页 Cancer Research on Prevention and Treatment
基金 云南省科技厅社会发展基金资助项目(2008CD203) 云南省社会发展科技计划-社会事业发展专项基金资助项目(2009CA009)
关键词 叉头框蛋白M1 结直肠腺瘤 结直肠癌 免疫组织化学
分类号 R735.3 [医药卫生—肿瘤]
  • 相关文献

参考文献19

  • 1Massagué J.G1 cell-cycle control and cancer [J].Nature, 2004, 432(7015):298-306. 被引量：1
  • 2Wang IC, Chen YJ, Hughes D, et al.Forkhead box M1 regulates the transcriptional network of genes essential for mitotic Progression and genes encoding the SCF (Skp2-1) ubiquitin ligase [J].Mol Cell Biol, 2005, 25(24): 10875-10894. 被引量：1
  • 3Costa RH.FOXM1 dances with mitosis [J].Nat Cell Biol, 2005, 7(2): 108-110. 被引量：1
  • 4Obama K, Ura K, Li M, et al.Genome-wide analysis of gene expression in human intrahepatic cholangiocarcinoma [J].Hepatology, 2005,41(6):1339-1348. 被引量：1
  • 5Wang Z, Banerjee S, Kong D, et al.Downregulation of Forkhead Box M1 transcription factor leadsto the inhibition of invasion and angiogenesis of pancreatic cancer cells [J].Cancer Res, 2007, 67(17): 8293-8300. 被引量：1
  • 6Francis RE, Myatt SS, Krol J, et al.FOXM1 is a downstream target and marker of HER2 overexpression in breast cancer [J].Int J Oncol, 2009, 35(1):57-68. 被引量：1
  • 7Wang IC, Meliton L, Tretiakova M, et al.Transgenic expression of the forkhead box M1 transcription factor induces formation of lung tumors [J].Oncogene, 2008, 27(30):4137-4149. 被引量：1
  • 8Teh MT, Wong ST, Neill GW, et al.FOXM1 is a downstream target of Gli1 in basal cell carcinomas[J].Cancer Res, 2002, 62(16): 4773-4780. 被引量：1
  • 9Yoshida Y, Wang IC, Yoder HM, et al.The forkhead box M1 transcription factor contributes to the development and growth of mouse colorectal cancer[J].Gastroenterology, 2007, 132(4): 1420-1431. 被引量：1
  • 10Kalin TV, Wang IC, Ackerson TJ, et al.Increased levels of the FOXM1 transcription factor accelerate development and progression of prostate carcinomas in both TRAMP and LADY transgenic mice [J].Cancer Res, 2006, 66(3):1712-1720. 被引量：1

二级参考文献40

  • 1Alexandra Zahn,Christoph Moehle,Thomas Langmann,Robert Ehehalt,Frank Autschbach,Wolfgang Stremmel,Gerd Schmitz.Aquaporin-8 expression is reduced in ileum and induced in colon of patients with ulcerative colitis[J].World Journal of Gastroenterology,2007,13(11):1687-1695. 被引量：13
  • 2Eichberger T, Regl G, Ikram M S, et al. FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma. J Invest Dermatol, 2004, 122(5):1180-1187 被引量：1
  • 3Freyaldenhoven B S, Fried C, Wielckens K. FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines. Gene, 2002, 294(1-2): 131-140 被引量：1
  • 4Fox S B, Brown P, Han C, et al. Expression of the forkhead transcription factor FOXP1 is associated with estrogen receptor α and improved survival in primary human breast carcinomas. Clin Cancer Res, 2004, 10(10): 3521-3527 被引量：1
  • 5Wolfrum C, Asilmaz E, Luca E, et al. Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature, 2004, 432(7020): 1027-1032 被引量：1
  • 6Lantz K A, Vatamaniuk M Z, Brestelli J E, et al. Foxa2 regulates multiple pathways of insulin secretion. J Clin Invest,2004, 114(4): 512-520 被引量：1
  • 7Wolfrum C, Shih D Q, Kuwajima S, et al. Role of Foxa2 in adipocyte metabolism and differentiation. J Clin Invest,2003, 112(3): 345-356 被引量：1
  • 8Purdom S, Chen Q M. p66(Shc): at the crossroad of oxidative stress and the genetics of aging. Trends Mol Med, 2003,9(5): 206-210 被引量：1
  • 9Nemoto S, Finkel T. Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. Science,2002, 295(5564): 2450-2452 被引量：1
  • 10Purdom S, Chen Q M. Linking oxidative stress and genetics of aging with p66Shc signaling and forkhead transcription factors. Biogerontology, 2003, 4(4): 181-191 被引量：1

共引文献41

同被引文献32

  • 1Sosa JA,Udelsman R. Papillary thyroid cancer[J].Surgical Oncology Clinics of North America,2006,(03):585-601.doi:10.1016/j.soc.2006.05.010. 被引量：1
  • 2How J,Tobah R. Explaining the increasing incidence of differentiated thyroid cancer[J].Canadian Medical Association Journal,2007,(1 1):1383-1384.doi:10.1503/cmaj.071464. 被引量：1
  • 3Puxeddu E,Moretti S. Clinical Prognosis in BRAF-Mutated PTC[J].Arq Bras Endocrinol Metab,2007,(05):737. 被引量：1
  • 4Kaliniehenko VV,Major ML,Wang X. FoxM1b transcription factor is essential for development of hepatocellular carcinomas and is negatively regulated by the p19ARF tumor suppressor[J].Genes and Development,2004,(07):830-850. 被引量：1
  • 5Madureim PA,Varshochi R,Constantinidou D. The Forkhead box M1 protein regulates the transcription of the estrogen receptor alpha in breast cancer ceils[J].Journal of Biological Chemistry,2006,(35):25167-25176. 被引量：1
  • 6Liu M,Dai B,Kang SH. FoxM1B is overexpressed in human glioblastomns and critic ally regulates the tumorigenicity of glioma cells[J].Cancer Research,2006,(07):3593-3602. 被引量：1
  • 7Wonsey DR,Follettie MT. Loss of the forkhead transcription factor FOXMl causes centrosome amplification and mitotic catastrophe[J].Cancer Research,2005,(12):5181-5189. 被引量：1
  • 8Petrovic V,Costa RH,Lau LF. FoxM1 regulates growth factorinduced expression of kinase-interacting stathmin (KIS) to promote cell cycle progression[J].Journal of Biological Chemistry,2008,(01):453-460. 被引量：1
  • 9Wang X,Quail E,Hung N J. Increased levels of forkhead box MlB transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver[J].Proceedings of the National Academy of Sciences(USA),2001,(20):11468-11473.doi:10.1073/pnas.201360898. 被引量：1
  • 10Wang Z,Banerjee S,Kong D. Down-regulation of Forkhead Box M1 transcription factor leads to the inhibition of invasion and angiogenesis of pancreatic cancer cells[J].Cancer Research,2007,(17):8293-8300. 被引量：1

引证文献4

二级引证文献9

肿瘤防治研究
2011年 第10期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部