摘要
目的探讨老年患者真菌感染的分布及耐药性,为临床合理用药提供依据。方法收集医院老年病房2010年6月-2011年6月临床送检标本,进行真菌分离、鉴定和药敏试验。结果 2290株真菌中,白色假丝酵母菌占57.7%,光滑假丝酵母菌占14.3%;真菌分离率较高的科室为呼吸科;检出真菌标本痰液占78.6%,尿液标本占10.1%;真菌对两性霉素B和5-氟胞嘧啶敏感率分别为99.0%和98.4%。结论老年病房真菌感染以白色假丝酵母菌为主,真菌感染率较高,应重视真菌病原学检查及药敏检测,为临床合理用药提供依据。
OBJECTIVE To explore the clinical distribution and drug resistance characteristics of pathogens from eldly fungal infection patients to provide the gist for clinical therapy. METHODS The clinical isolates gathered from inpatients in geriatric ward during Jun 2010 to Jun 2011 were identified and tested for drug resistance. RESULTS Among 2 290 strains of fungi,1322 strains were Candida albicans（57.7%）,336 strains were C.tropicalis（14.7%）and 328 strains were C.glabrata（14.3%）.The clinical departments with highest infective rate was department of Respiratory;The highest detection rate of 78.3% was in sputum specimens,followed by 10.1% in the urine.Susceptibility results showed that amphotericin B was the most sensitive drug with the sensitivity rate of 99.0%. CONCLUSION In geriatric wards,the majority isolated fungal strain is C.albicans.The fungal infection is severe.It should pay attention to the fungi detection and rational use of antifungal agents.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第22期4848-4850,共3页
Chinese Journal of Nosocomiology
关键词
老年
真菌感染
药敏试验
Geriatric
Fungal infection
Drug susceptibility test
