摘要
目的:探讨自固化磷酸钙人工骨(ACPC)载药核心块状同种异体骨治疗小段创伤性骨髓炎骨缺损的临床意义。方法:应用ACPC载药核心块状同种异体骨治疗36例小段创伤性骨髓炎患者,观察患者手术前后的全身及局部组织反应、ESR及CRP、X线摄片和CT扫描;随访时间为13～24个月,平均18.5个月。结果:全部患者未见明显全身反应,31例局部软组织愈合好,窦道消除,X线显示ACPC与骨髓炎清除区局部骨质直接愈合,CT示界面处未见间隙存在,基本恢复骨缺损处的解剖形状,Ⅰ期治愈率为86.1%。另5例需要第二次清创、ACPC载药核心块状同种异体骨植入填充手术后获治愈。结论:ACPC载药核心块状同种异体骨对小段创伤性骨髓炎骨缺损具有治疗彻底、骨缺损修复好、能较好恢复负重肢体功能的优点。
Objective：To explore the clinical meaning of ACPC drug-loaded core lump allogeneic bone treating bone defects of traumatic occlusion osteomyelitis. Methods：With ACPC drug-loaded core lump allogeneic bone treating 27 cases of traumatic occlusion osteomyelitis, obselved all over the body and local tissue reaction, ESR and CRP, X-ray and CT scaning result before and after operations. Then followed 18.5 months in average, from 13 to 24 months. Reslut：All the cases were not found obvious general reaction. There were 31 cases with good healing of local parenehyma, sinus elimated, X-ray result showed that ACPC fused with local sclerotin of osteomyelitis clean area, CT reslut showed that no grudges existed and nearly recoveryed the anatomy shape of bone defects. The cure rate of Ⅰ stage was 86.1%. Conclusion： ACPC drug-loaded core lump allogeneic bone treating bone defects of traumatic occlusion osteomyelitis, it has good qualities such as thorough treatment, well repairing bone defects and better recoverying weight loading limbs function.
出处
《广州医学院学报》
2011年第3期58-60,共3页
Academic Journal of Guangzhou Medical College
关键词
创伤性骨髓炎
骨缺损
同种异体骨
自固化磷酸钙人工骨
traumatic occlusion osteomyelitis
bone defects
allogeneic bone
auto-solidification calcium phosphate cement （ACPC）
