摘要
目的:分析影响急性冠脉综合征高龄患者PCI术后预后的危险因素。方法:选取3年来我科住院72例接受PCI术的急性冠脉综合征患者,按年龄分为:高龄组,年龄≥75岁,共36例;低龄组,年龄<75岁,共36例。分析高龄患者PCI术后的HbA1c、NT-proBNP、血小板聚集率(PAGR)与随访1年后LVEF、LVEDd值的相关性。比较两组的主要不良心脏事件(MACE),即再梗塞率及死亡率之间的差异。结果:高龄患者的NT-proBNP、PAGR与LVEF值呈负相关关系,相关系数为-0.891和-0.901,与LVEDd值呈正相关关系,相关系数为0.857和0.924。而HbAlc与LVEF、L-VEDd值无明显相关性。两组的MACE(再梗塞率及死亡率)部存在差异性,P值分别为0.0148与0.0254。结论:急性冠脉综合征高龄患者PCI术后MACE较低龄患者发生率高,且心脏功能与NT-proBNP及PAGR有相关性。
Objective：To analyze the risk factors affecting on prognosis of aged patients with acute coronary syndromct ACSI post- PCI opcration.Methods：A total of 72 patients with ACS in our hospital received PCI operation were divided into two groups, senility group（age〉75） and young group（age〈75）, each group involved 36 patients, according to the age. The factors of HbAlc. NT-proBNP and platelet aggregauon rate（PAGR） were anamyzed the correlation to the value of LVEF ,and LVEDd after 1 year follow-up.And major adverse cardiac events（MACE）, such as recurrent MI and mortality death rate, were compared between two groups. Results：The negative correlation coefficients of NT-proBNP and PAGR with LVEF were -0.891 and -0.901. respectively. The positive correlation coefficients of NT-proBNP and PAGR with LVEF were 0.857 and 0.924. respectively. The rate of MACE was different between wen groups, and the values of P were 0.0148 and 0.0254. respectively. Conclusion：The rate of MACE in aged patients with ACS received PCI operation was higher than young patients, and eardic ruction had correlation to NT-oroBNP and PAGR.
出处
《中国医药导刊》
2011年第8期1289-1290,共2页
Chinese Journal of Medicinal Guide
关键词
急性冠脉综合征
经皮冠状动脉介入术
高龄
预后
Acute coronary syndrome
Percutaneous coronary intervention
Aged patients
Prognosis
