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CO_2激光联合中药治疗小儿呼吸道乳头状瘤临床疗效观察 被引量:1

Clinical Investigation of the CO_2 Laser and Chinese Traditional Medicine to Treat Juvenile-onset Recurrent Respiratory Papillomatosis
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摘要 目的:探讨应用CO2激光手术联合中药治疗小儿呼吸道乳头状瘤的疗效。方法:选取来本院手术治疗的年龄小于14岁的呼吸道乳头状瘤患者116例,并随机分为观察组和对照组。两组均采用CO2激光手术治疗,观察组在手术后同时给予中药治疗,观察两组患者中药治疗前后Derkay评分和手术间隔时间,并应用荧光定量PCR法检测中药治疗前后肿瘤组织中HPV6/11的含量。结果:观察组与对照组相比,手术间隔时间延长,Derkay评分降低,差异有统计学意义;观察组中药治疗前后HPV-DNA含量降低,差异有统计学意义,对照组无明显变化,差异无统计学意义。结论:CO2激光联合中药治疗小儿呼吸道乳头状瘤是一种有效的治疗方法。 Objective:To observe the clinical effect of the union of CO2 laser surgrey and Chinese Traditional Medicine to treat juvenile-onset recurrent respiratory papillomatosis.Methods:Selected for patients with respiratory papillomatosis in our hospital less than 12 years of age and stochastically divided them into the observation group and control group.Both of these two groups received the treatment of the CO2 laser surgery,after that,the observation group was given treatment with Chinese Traditional Medicine.Detecting HPV-DNA contents of HPV6/11 using Fluorescence quantitative PCR(FQ-PCR)in tumor tissue before and after treatment of Chinese medicine.Results:Compared with the control group,time between surgery of observation group is longer,and Derkay score is lower,the difference reached statistical significance;HPV-DNA contents in observation group was reduced after treatment with Chinese Traditional Medicine,the difference reached statistical significance.There is no change in the control group.Concousion:It is an effective treatment to treat the juvenile-onset recurrent respiratory papillomatosis by means of the union treatment of the CO2 laser and Chinese Traditional Medicine.
出处 《辽宁中医药大学学报》 CAS 2011年第11期99-101,共3页 Journal of Liaoning University of Traditional Chinese Medicine
基金 北京市中医管理局资助项目(JJ2008-002) 北京市卫生局 北京市中医管理局青年科学研究资助项目(QN2008-4)
关键词 乳头状瘤 免疫 激光 中药 Papilloma immunity C02 laser Chinese traditional medicine
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