摘要
目的:评价基层医生采用醋酸/碘试验在农村地区筛查宫颈癌及宫颈癌前期病变的效果。方法:以新疆和田县30～59岁已婚妇女作为对象,进行以人群为基础的子宫颈癌筛查,用5%醋酸染色后肉眼观察(VIA)和2%碘染色后肉眼观察(VIA),结果异常者进行阴道镜活检病理诊断。筛查妇女进行基本信息调查。采用同样的程序对人群进行复查,对比第1年,第2年的筛查及随访结果,评价该方案的效果。结果:2007～2009年总筛查人数5 565人,2007～2008年和田县巴格期镇筛查3565人,2008～2009年和田县洛浦镇筛查2 000人。巴格期镇第一轮筛查CINⅠ检出率为0.16%,CINⅡ0.14%,CINⅢ0.53%,宫颈癌0.22%;第二轮筛查(复查)CINⅠ检出率为0.20%,CINⅡ0.17%,CINⅢ0.13%,宫颈癌检出率为0。洛浦县第一轮筛查:ClNⅠ检出率0.6%,CINⅡ0.15%,ClNⅢ0.4%,宫颈癌0.45%;第二轮筛查ClNⅠ0.33%,CINⅡ0.11%,CINⅢ0.16%,宫颈癌检出率为0,筛查CINⅡ以上总阳性率1.24%。不同县两轮筛查中均第一年发现癌症,第二年没有,第一轮筛查CINⅡ以上的比率分别为82.00%(巴格期镇)和81.40%(洛浦县)。在查出的宫颈病变及宫颈癌的平均年龄分别CINⅠ42岁,CINⅡ43岁,CINⅢ45岁,宫颈癌45岁。结论:VIA/VILI方法短时间内易掌握、费用低、操作简单、出结果快,不依赖于仪器设备,在和田宫颈癌筛查中的到了良好的效果,发现的阳性患者给予及时治疗,在降低宫颈癌死亡率方面也有一定作用,可以在农村地区推广应用。
Objective：To evaluate the effects of acetic acid staining and iodine staining used by grass-roots doctors in screening of cervical cancer and precancerous lesion of cervical cancer in rural area.Methods：The married women aged 30~59 years old were selected from Hetian county of Xinjiang as study objects,then cervical cancer screening was conducted based on population,visual inspection based on 5% acetic acid staining and 2% iodine staining was carried out,the cases with abnormal results received biopsy under colposcope and pathological examination.The basic data of the women were investigated.The women were reexamined according to the same process,the screening results and follow-up results in the first and second year were compared,the effect of the project was evaluated.Results：5 565 cases were screened from 2007 to 2009,3 565 cases were screened in Bageqi town of Hetian county from 2007 to 2008,2 000 cases were screened in Luopu town of Hetian county from 2008 to 2009.The detection rates of CIN Ⅰ,CIN Ⅱ,CIN Ⅲ and cervical cancer during screening for the first time in Bageqi town were 0.16%,0.14%,0.53% and 0.22%,respectively.The detection rates of CIN Ⅰ,CIN Ⅱ,CIN Ⅲ and cervical cancer during screening for the second time in Bageqi town were 0.20%,0.17%,0.13% and 0,respectively.The detection rates of CIN Ⅰ,CIN Ⅱ,CIN Ⅲ and cervical cancer during screening for the first time in Luopu town were 0.6%,0.15%,0.4% and 0.45%,respectively.The detection rates of CIN Ⅰ,CIN Ⅱ,CIN Ⅲ and cervical cancer during screening for the second time in Luopu town were 0.33%,0.11%,0.16% and 0,respectively.The total positive rate of above CIN Ⅱ lesions was 1.24%.In the two towns,cervical cancer was found during screening for the first time,not for the second time,the proportions of above CIN Ⅱ lesions during screening for the first time were 82.00%（Bageqi town） and 81.40%（Luopu town）.Among the cases found with cervical lesions and cervical cancer,the average ages were 42 years（CIN Ⅰ）,43 years
出处
《中国妇幼保健》
CAS
北大核心
2011年第28期4332-4334,共3页
Maternal and Child Health Care of China
基金
中央转移支付宫颈癌早诊早治项目〔2007-2009〕
关键词
子宫颈癌
醋酸染色
碘染色筛查
农村
Cervical cancer
Acetic acid staining
Iodine staining screening
Rural area
