摘要
目的观察雷贝拉唑联合莫沙必利治疗返流性食管炎的临床疗效。方法将46例反流性食管炎患者,随机分为治疗组23例和对照组23例,两组均服用莫沙必利,观察组再给予雷贝拉唑。结果治疗8周后,治疗组症状改善优于对照组,临床疗效总有效率95.6%,两组比较有显著性差异(P<0.05),内镜下疗效观察结果显示:治疗组显著优于对照组,总有效率91.3%,两组比较有显著性差异(P<0.05)。结论雷贝拉唑与雷尼替丁相比较,疗效更显著,能迅速改善症状,是治疗RE的有效药物,值得临床推广。
Objective To observe rabeprazole joint mosapride treatment of reflux esophagitis clinical efficacy.Methods 46 patients with reflux esophagitis patients,randomly divided into treatment group of 23 patients and control group of 23 patients.Both groups were taking mosapride.In the observation group and then give rabeprazole.Results After 8 weeks,symptoms improved treatment group than the control group,clinical total effective rate was 95.6%,the two groups was significant difference（P0.05）.Efficacy of endoscopic treatment group showed significantly better than the control group,total efficiency of 91.3%,the two groups was significant difference（P0.05）.Conclusion Rabeprazole compared with ranitidine,more pronounced effect,can rapidly improve the symptoms and be effective drug for treatment of RE,should be worthy of promotion.
出处
《黑龙江医学》
2011年第9期685-687,共3页
Heilongjiang Medical Journal
