摘要
近年来,计算分光光度法得到了迅速的发展,有关各种新方法应用的报道层出不穷,如最小二乘法、线性规划、卡尔曼滤波、因子分析及P-矩阵法等,使得以往用经典分析方法难以测定的复方制剂问题能够在数学及微机的辅助下得以解决。但迄今为止,同时测定的组分数目一般均小于或等于四个。
Kalman filtering spectrophotometry was investigated to assay the contents of vitamin B_1, vitamin B_6, chlordiazepoxide, dihydralazine sulfate, promethazine hydrochloride and hydrochlorothiazide in compound reserpine tablets consisting of 10 components. Absorption proportionality constant for each component was obtained by the application of non-negative least square method. The average recoveries for each were 97～103% with CV% ≤6.9 except vitamin B_1 (n=11).
出处
《药学学报》
CAS
CSCD
北大核心
1990年第1期77-80,共4页
Acta Pharmaceutica Sinica
基金
国家自然科学基金
关键词
卡尔曼滤波
降压片
含量测定
Vitamin B_1
Vitamin B_6
Promethazine hydrochloride
Chlordiazepoxide
Dihydralazine sulfate
Hydrochlorothiazide
Kalman filtering spectrophotometry
