摘要
目的:观察氨酚羟考酮片(泰勒宁)配合消肿止痛合剂对人工全膝关节置换术(TKA)后患者的镇痛效果。方法:将50例TKA患者随机分为研究组及对照组,研究组术后采用氨酚羟考酮片配合消肿止痛合剂进行镇痛,对照组术后口服萘普生缓释胶囊镇痛,2组患者均维持镇痛3天。术后记录患者在静息时及活动时的VAS评分(视觉模拟评分系统)。结果:研究组和对照组同组间不同时点VAS评分改善比较(P<0.05)存在统计学差异,表明2组治疗均有一定疗效;研究组术后72小时VAS评分均低于对照组(P<0.05),说明研究组在TKA术后镇痛效果上与对照组存在显著性差异。术后7天,2组不存在显著性差异。结论:氨酚羟考酮片配合消肿止痛合剂对TKA术后的镇痛疗效肯定。
Objective：to observe the analgesic effects of oxycodone and acetaminophen tablets and mixture of alleviating swelling and relieving pain on the patients after TKA.Method：50 TKA patients are randomly divided into research group and control group.The postoperative patients in research group receive oxycodone and acetaminophen tablets and mixture of alleviating swelling and relieving pain,while the ones in the control group orally take naproxen sustained release capsule.Both of the groups maintain analgesia for three days.The postoperative visual analog scale（VAS） at rest and movement are recorded.Result：There are significant differences when VAS of research group and control group are compared in the same group at different hours（P0.05）,which shows there are certain efficacy of both groups＇ treatment.72 h VAS of research group is lower than control groupP0.05,which illustrates there is significant difference on analgesia after TKA between research group and control group.7 days after the operation,there is no significant difference between two groups.Conclusion：the analgesic efficacy of oxycodone and acetaminophen tablets and mixture of alleviating swelling and relieving pain after TKA is significant and they deserve further clinical application.
出处
《西部中医药》
2011年第10期4-6,共3页
Western Journal of Traditional Chinese Medicine
关键词
全膝人工置换术
氨酚羟考酮片
消肿止痛合剂
镇痛
疗效
total knee arthroplasty（TKA）
oxycodone and acetaminophen tablets
mixture of alleviating swelling and relieving pain
analgesia
effects
