摘要
目的:探讨血清超敏C反应蛋白(Hs-CRP)及纤维蛋白原(FIB)在糖尿病足感染患者(DFI)中的变化及临床意义。方法:分别测定42例糖尿病足患者和50例健康对照组人员空腹血糖(FPG)、Hs-CRP和FIB。结果:糖尿病足感染患者FPG为(12.32±5.69)mmol/L,显著高于对照组的(4.65±1.51)mmol/L(P<0.01);Hs-CRP为(5.24±4.64)mg/L,显著高于对照组的(1.45±1.96)mg/L(P<0.01);FIB为(4.24±1.01)g/L,显著高于对照组的(2.90±0.80)g/L(P<0.01)。结论:糖尿病足感染患者Hs-CRP和FIB的升高与糖尿病足密切相关。Hs-CRP和FIB可作为糖尿病足感染患者诊断及其转归的敏感指标,对于临床症状非典型患者更有临床意义。
Objective： To investigate the change of high sensitive C-reactive protein（Hs-CRP） and Fibrinogen（FIB） in the patients with diabetic foot infection and its clinical significance.Methods： The FPG,Hs-CRP and FIB levels of patients with diabetic foot infection and healthy people were detected respectively.Results： FPG,Hs-CRP and FIB in diabetic foot group [（12.32±5.69） mmol/L,（5.24±4.64） mg/L,（4.24±1.01） g/L] were higher than that of healthy people [（4.65±1.51） mmol/L,（1.45±1.96） mg/L,（2.90±0.80） g/L]（P0.01）.Conclusion： The increase of Hs-CRP and FIB in diabetic foot group may be closely related to the development of diabetic foot infection.Hs-CRP and FIB can be as the sensitive index to diagnose DFI and its outcome.It is more significant in the patients with atypical clinical symptom.
出处
《中国医药导报》
CAS
2011年第29期158-159,共2页
China Medical Herald
关键词
糖尿病足
感染
超敏C反应蛋白
纤维蛋白原
Diabetic foot
Infection
High sensitive C-reactive protein
Fibrinogen
