摘要
目的:优选桂枝颗粒的成型辅料。方法:考察不同种类和比例的辅料对桂枝颗粒成型性、溶化性和吸湿性的影响,并用综合评分法筛选出制备桂枝颗粒的最优辅料及辅料比例。结果:制备桂枝颗粒的最优辅料为糊精和乳糖,两者使用比例为1∶1。结论:采用该方法制成的桂枝颗粒成型性、溶解性好,不容易吸湿,效果理想。
Objective：To optimize the formative excipients for Guizhi granule.Method：Effects of different types and ratios excipients on the formation,moisture absorption and relative critical humidity of Guizhi granule were examined,and the optimal excipients as well as formula were selected by adoption of the comprehensive scoring method.Result：The optimal excipient for preparation of Guizhi granule were dextrin and lactose,and the ratio of between the two was 1∶1.Conclusion：The Guizhi granule thus prepared is ideal：good in shape,easy to dissolve and not liable to moisture absorption.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第20期45-47,共3页
Chinese Journal of Experimental Traditional Medical Formulae
关键词
桂枝颗粒
成型辅料
吸湿性
Guizhi granule
formative excipients
moisture absorption
