摘要
目的分析ICU鲍氏不动杆菌(ABA)耐药性和临床特点,为预防和控制ABA的感染提供依据。方法对医院2008年1月-2010年12月ICU患者送检标本中分离的鲍氏不动杆菌在病区分布与耐药性进行回顾性分析。结果 ICU 2008-2010年鲍氏不动杆菌的检出率逐年增加,共分离出804株鲍氏不动杆菌,主要来源于痰液,占92.8%;ABA对亚胺培南、美罗培南的耐药率日渐增高,从2008年的14.4%和28.9%上升至2010年的91.7%、94.4%,对其他抗菌药物耐药率均明显上升。结论 ABA在ICU的感染较为严重,而且耐药性很高;必须采取相应的防治和监控措施,预防ABA的高耐药性和多药耐药性造成的医院感染。
OBJECTIVE To analyze the condition of drug resistance and clinical characteristics of Acinetobacter baumannii（ABA） in ICU ward for the purpose of providing reference with lower infection.METHODS The distribution of endemic areas and drug resistance of A.baumannii isolated from the specimens of the inpatients in ICU ward from Jan 2008 to Dec 2010 were analyzed retrospectively.VITEK automated system was applied to the identification and drug sensitive test.The data were statistically an analyzed by WHONET 5.5 software.Drug resistance of ABA to common antibacterials was analyzed according to CLSI.RESULTS The isolation rate was increased annually in ICU ward from 2008 to 2010.A total of 804 ABA strains were isolated mainly from sputum,accounted for 92.8%.The drug resistant rate of ABA to imipenem and meropenem were increased gradually from 14.4% and 28.9% to 91.7% and 94.4%,respectively.The resistant rates of ABA to other antibacterial agents were in an up trend.CONCLUSION A.baumannii in ICU infection is most serous and the drug resistance rate is much higher.It must take preventive measures to monitoring of drug resistance in ABA and to prevent nosocomial infections caused by multidrug resistant strains.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第20期4379-4380,共2页
Chinese Journal of Nosocomiology
关键词
鲍氏不动杆菌
耐药性
重症监护病房
Acinetobacter baumannii
Drug resistance
Intensive care unit
