摘要
目的研究足月妊娠妇女宫颈阴道分泌物中胎儿纤维连接蛋白(fetal Fibronectin,fFN)对普贝生引产效果的影响。方法选择82例有引产指征,且无母婴禁忌证的足月妊娠产妇。测定宫颈阴道分泌物中fFN,同时行宫颈Bishop评分,Bishop评分≤6分者,阴道后穹隆放置普贝生1枚。结果用药到临产平均时间、总产程时间、临产率,fFN阳性组均优于fFN阴性组,两组差异均有统计学意义(P<0.05);胎儿宫内窘迫发生率fFN阳性组高于fFN阴性组,两组差异有统计学意义(P<0.05);经阴道分娩率两组比较差异无统计学意义(P>0.05)。结论在足月妊娠妇女宫颈Bishop评分≤6分者中,只有阴道分泌物fFN阴性用普贝生引产才是安全的。
Objective To study the effect of fetal fibronectin（fFN） on induced delivery by Propess for term pregnancy. Methods Term pregnancy cases among 82 term pregnancy chosen with indications of induced and without maternal and infantile contraindications were placed one piece of Propess in posterior fornix if fFN of vaginal secretions was examined and Bishop cervix score was≤ 6. Results Average time from the medication to the parturient, total stage of labor time, parturient rate in positive fFN group were better than those in negative fFN group that the difference was significant （ P 〈0. 05 ）. Incidence rate of fetal distress in uterus in positive fFN group was higher than that in negative fFN group that the difference was significant （ P 〈 0.05 ）. The difference of vaginal delivery rate was no significantly （ P 〉 0. 05 ）. Conclusion It is safe that Propess is given to term pregnancy women with induced abortion when fFN of vaginal secretions is negative.
出处
《中国计划生育和妇产科》
2011年第5期64-67,共4页
Chinese Journal of Family Planning & Gynecotokology
