摘要
运用文献资料法,分析肥胖症与动脉粥样硬化的关系。肥胖引起脂肪组织分泌的细胞因子,如C反应蛋白、脂联素、瘦素、血管内皮生长因子、肿瘤坏死因子-α、白细胞介素-6等水平异常,可加速血管内皮炎性反应,与肥胖密切相关的脂代谢紊乱、血液流变性异常、胰岛素抵抗,亦可诱发血管内皮功能障碍,从多个环节加速动脉粥样硬化的进程。对肥胖症患者早期进行运动干预,有望阻止动脉粥样硬化病灶的进一步发展,降低动脉粥样硬化发生的危险性。
With the method of literature review, this paper probes into the relationship between obesity and atherosclerosis. Recent studies have found that obesity may initiate inflammatory reaction of vascular endothelium and give rise to lipid metabolic disturbance, change of hemal flow, insulin resistance, and dysfunction, promoting the occurrence and development of atherosclerosis. The exercise intervention on obesity people in early stage should be of great importance to the prevention of atherosclerosis.
出处
《上海体育学院学报》
CSSCI
北大核心
2011年第5期52-56,共5页
Journal of Shanghai University of Sport
基金
上海市重点学科(第3期)建设资助项目(S30802)
关键词
肥胖症
动脉粥样硬化
炎症因子
血脂
胰岛素抵抗
obesity
atherosclerosis
inflammatory factor
blood lipid
insulin resistance
