摘要
目的探讨老年慢性阻塞性肺疾病（chronicobstructivepulmonarydisease，COPD）合并陈旧性肺结核患者抑郁相关影响因素。方法对比分析老年COPD合并陈旧性肺结核120例、单纯c（）PD110例患者的一般资料，肺功能，血气分析结果，COPDAssessmentTest（CAT）、呼吸困难量表（MediealResearchCouncildyspneascale，MRC）、老年抑郁量表（GeriaricDepressionScale，GDS）评分，及COPD合并陈旧性肺结核GDS评分与以上指标的相关性。结果老年COPD合并陈旧性肺结核组抑郁发病率，CAT、MRC、GDS评分较COPD组高（P〈0．05），GDS评分与吸烟指数、PaCO2、CAT、MRC评分呈正相关，与FEV．／FVC、FEV。％pred、PaO2呈负相关。结论COPD合并陈旧性肺结核组与COPD组相比，抑郁的发病率更高，生活质量更差，其GDS评分与吸烟指数、PaCO2、CAT、MRC评分呈正相关，与FEV，／FVC、FEV，％pred、PaO2呈负相关。
Objective To investigate the related factors of depression in elderly patients with chronic obstructive pulmonary disease （COPD） combined with old pulmonary tuberculosis. Methods 120 elderly patients with COPD combined with old pulmonary tuberculosis and 110 patients with COPD were questioned with general information, lung function and arterial blood gas analysis results, which were respectively compared. Quality of life （COPD Assessment Test, CAT）, dyspnea scale and depression status were respectively assessed using CAT, Medical Research Council dyspnea scale （MRC） and the Geriaric Depression Scale （GDS）, which were respectively compared. The correlation between the GDS score and smoking index, lung function, arterial blood gas analysis results, CAT score and MRC score were analized. Results The incidence rate of depression in the elderly patients with COPD combined with old pulmonary tuberculosis was higher than that of the COPD group. Meanwhile. COPD with old tuberculosis had more CAT score （ P 〈0.05）, more MRC score and the GDS score （ P 〈0.05）. The GDS score of COPD with old tuberculosis had positive correlation with Smoking index, PaCO2, CAT score,MRC score, and negative correlation with FEV,/FVC, FEV1% pred, PaO2. Conclusions COPD with old tuberculosis had higher incidence rate of depression, and poorer quality of life. And the GDS score of COPD with old tuberculosis had positive correlation with smoking index, PaCO2, CAT score, MRC score,and negative correlation with FEV,/FVC,FEV1 % pred,PaO2.
出处
《国际呼吸杂志》
2011年第19期1463-1465,共3页
International Journal of Respiration
关键词
慢性阻塞性肺疾病
陈旧性肺结核
抑郁症
老年
Chronic obstructive pulmonary disease
Old pulmonary tuberculosis
Depression
Elderly
