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逆行标记法研究颈脊神经节至交感神经节的神经反射通路 被引量:7

Neural reflex pathway from cervical spinal ganglia to cervical sympathetic ganglia: an in vivo retrograde labeling in the rabbit
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摘要 目的分析颈交感神经节和颈脊神经节之间的神经纤维联系,探讨颈性眩晕发病的神经反射基础。方法 48只新西兰兔随机分为颈上交感神经节组和颈下交感神经节组及相应对照组,于颈上或颈下交感神经节内分别注入荧光金溶液或生理盐水,分别于存活4、8d后取出双侧颈脊神经节C2~C8,制备冷冻切片并进行荧光显微镜观察分析。结果颈上交感神经节组在同侧C2~C5脊神经节中出现荧光金标记神经元,以C3和C4脊神经节中标记神经元为多;颈下交感神经节组在同侧C5~C8脊神经节中出现标记神经元,以C6和C7为多。结论颈交感神经节和颈脊神经节之间存在直接的神经纤维联系,且有一定的分布规律,这些联系可能是颈性眩晕的神经解剖学基础。 Objective To study the neural connections between cervical sympathetic ganglia and cervical spinal ganglia, and explore the neuroanatomical basis of the pathogenesis of cervical vertigo. Methods New Zealand rabbits were randomly divided into superior, inferior cervical sympathetic ganglia and control groups. Fluoro-gold (FG) or normal saline was injected into the superior or inferior cervical sympathetic ganglia. At 4 or 8 days after injection, the bilateral spinal ganglia were removed, cryo-sectioned and observed under a fluorescence microscope. Results FG labeled neurons were found in the ipsilateral C2-C5 spinal ganglia and more FG labeled neurons were observed in C3 and C4 spinal ganglia in the superior cervical sympathetic ganglia group. In the inferior cervical sympathetic ganglia group, there were FG labeled neurons in the C5-C8 spinal ganglia and more FG labeled neurons were found in C6 and C7 spinal ganglia. Conclusion Neural reflex arch between cervical spinal and cervical sympathetic ganglia was found, which may provide an important neuroanatomical basis for the cervical vertigo.
出处 《解剖学报》 CAS CSCD 北大核心 2011年第5期614-617,共4页 Acta Anatomica Sinica
关键词 脊神经节 颈上交感神经节 颈下交感神经节 荧光金 颈性眩晕 神经反射弧 逆行追踪 新西兰兔 Spinal ganglion Superior cervical ganglion Inferior cervical ganglion Fluoro-gold Cervical vertigo Reflex arc Retrograde labeling New Zealand rabbit
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