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膳食蛋白质对高脂血症者血清脂质的影响 被引量:4

Effect of dietary protein on serum lipid profile in hypercholesterolemic people
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摘要 目的观察大豆蛋白对高血脂症人群血清脂质浓度的影响及膳食蛋白质与血脂的关系。方法招募单纯高脂血症志愿者90人,随机分为大豆分离蛋白组和酪蛋白组,在不改变饮食及运动习惯的基础上,每天分别补充24g酪蛋白和18g大豆分离蛋白+6g酪蛋白混合物,共8周。实验前和结束时,测量身高、体重、腰臀围,测定血清脂质浓度。结果 (1)大豆蛋白组体重和体质指数有所下降(P<0.05),酪蛋白组腰臀比减小(P<0.05)。(2)大豆蛋白组干预后ApoB和TC/HDL-C显著下降(P<0.05),而酪蛋白组TC、LDL-C和ApoB显著下降(P<0.05)。(3)膳食蛋白质摄入量与血清TC降低百分数呈显著负相关(r=-0.419,P<0.01),植物蛋白的摄入量与血清总胆固醇下降的百分数呈显著正相关(r=0.521,P<0.01)。结论膳食蛋白质来源和量会影响大豆蛋白对血脂的作用。 Objective To observe the effect of soy protein on the concentration of serum lipids in hypercholesterolemic people and the correlation between dietary protein and serum lipids.Methods Ninety healthy hypercholesterolemic volunteers were given beverages contained either 24 g of casein or 18 g of soy protein plus 6 g of casein by random daily for 8 weeks without change of their habitual life.Body height,body weight,waist and hip circumference and serum lipids were measured before and after the study.Result(1)The body weight and body mass index of subjects in the soy group were decreased slightly but significantly(P0.05),while the waist-to-hip circumference of subjects in casein group was decreased(P0.05).(2)ApoB and TC/HDL-C ratio were significantly reduced after consuming soy protein beverages for 8 weeks(P0.05),while in casein group,TC,LDL-C and ApoB were reduced significantly(P0.05).(3)The reduction in TC concentration was negatively correlated with the quantity of dietary protein intake(r=-0.419,P0.01),whereas it was positively correlated with the quantity of vegetable protein intake(r=0.521,P0.01).Conclusion The effect of soy protein on serum lipids could be influenced by the source and quantity of dietary protein.
出处 《卫生研究》 CAS CSCD 北大核心 2011年第5期601-603,共3页 Journal of Hygiene Research
关键词 膳食蛋白质 血脂 大豆蛋白 酪蛋白 高脂血症 dietary protein serum lipids soy protein casein
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